个人概况：
姓名：张天富 性别：男
职称：副教授 导师资格：硕士生导师
单位：广州医科大学生物医学工程学院
学历：博士 毕业院校：香港科技大学
招生专业：生物医学工程、药学
电子邮件：zhangtf@gzhmu.edu.cn
通信地址：广州医科大学番禺校区教学实验楼A区
研究方向
1. 具有聚集诱导发光（AIE）性质的多功能荧光探针的设计与开发
2. 肿瘤实时荧光成像示踪和光动力/光热治疗
3. 针对细菌感染的追踪和光动力/光热杀伤治疗
4. 以光疗为基础，开发光疗/免疫治疗、光疗/放化疗等联合治疗体系
本人从事生物医学工程和药学方面的教学和科研工作，主要研究致力于开发具有AIE性质的多功能有机发光材料用于癌症、细菌感染等重大疾病的多模态诊断和治疗。目前发表SCI高水平论文20篇(影响因子＞10)。相关成果已申请美国专利2项,中国专利1项。
所获奖项/荣誉（有科研、教学奖可以填）
1. Outstanding Scholars in Cardiovascular Engineering Award，2022年
2. COCHE心脑血管工程杰出学者奖铜奖，2021年
3. 最佳海报奖及最佳报告入选，2019亚洲化学联盟国际会议，2019年
4. 最佳墙报奖，第一届华人聚集诱导发光学术研讨会，2018年
主持科研/教学项目
广州医科大学“南山学者”高层次引进人才项目。
部分代表性第一和通讯作者论文：
1. Tianfu Zhang#, Xiaoyu Chen#, Congmin Yuan, Xiaobin Pang, Ping Shangguan, Lulu Han, Yisheng Liu, Jianwei Sun, Jacky W. Y. Lam, Jiefei Wang,* Bingyang Shi,* Ben Zhong Tang* Design of NIR AIEgens for In Vivo Theranostics of Alzheimer’s Disease: BBB Penetration, Fibrosis Inhibition and β-Amyloid Disassembly. Angew. Chem. Int. Ed. 2023, 62, e202211550. (影响因子：16.8)
2. Tianfu Zhang#, Zeming Liu#, Wenxue Tang#, Meng Lyu, Jacky Wing Yip Lam, Qinqin Huang,* Ben Zhong Tang* Mitochondria-Targeting Type I AIE Photosensitizer Combined with H2S Therapy: Uninterrupted Hydroxyl Radical Generation for Enhancing Tumor Therapy. Nano Today 2022. 46, 101620. (影响因子：19.0)
3. Tianfu Zhang#, Jianyu Zhang#, Fu-Bing Wang#, Hui Cao, Daoming Zhu, Xiaoyu Chen, Changhuo Xu, Xueqin Yang, Wenbin Huang, Zhaoyu Wang, Jiefei Wang, Zikai He, Zheng Zheng,* Jacky Wing Yip Lam,* and Ben Zhong Tang* Mitochondria-Targeting Phototheranostics by Aggregation-Induced NIR-II Emission Luminogens: Modulating Intramolecular Motion by Electron Acceptor Engineering for Multi-Modal Synergistic Therapy. Adv. Funct. Mater. 2022, 2110526. (影响因子：19.9)
4. Tianfu Zhang#,* Yanlin Deng#, Sylvia Yang Liu, Song Lin Chua,* Ben Zhong Tang,* Bee Luan Khoo* Bacterial Targeted Photosensitizers with Aggregation-induced Emission Property Synergistically Promote Chemotherapy for the Treatment of Inflammatory Cancer. Chem. Eng. J. 2022, 447, 137579. (影响因子：13.3)
5. Tianfu Zhang#, Yuanyuan Li#, Zheng Zheng, Ruquan Ye, Yiru Zhang, Ryan T.K. Kwok, Jacky W. Y. Lam and Ben Zhong Tang*. In Situ Monitoring Apoptosis Process by a Self-Reporting Photosensitizer. J. Am. Chem. Soc. 2019, 141, 5612-5616. (影响因子：16.8, 2018-2019年JACS高引论文、ESI高被引论文)
6. Shipeng Ning,# Tianfu Zhang#, Meng Lyu, Jacky W. Y. Lam, Daoming Zhu,* Qinqin Huang,* Ben Zhong Tang* A type I AIE photosensitiser-loaded biomimetic nanosystem allowing precise depletion of cancer stem cells and prevention of cancer recurrence after radiotherapy. Biomaterials 2023, 295, 122034. (影响因子：15.3)
7. Daoming Zhu#, Tianfu Zhang#, Yang Li, Chunyu Huang, Meng Suo, Ligang Xia, Youhua Xu,* Guoxin Li,* Ben Zhong Tang* Tumor-derived exosomes co-delivering aggregation-induced emission luminogens and proton pump inhibitors for tumor glutamine starvation therapy and enhanced type-I photodynamic therapy. Biomaterials 2022, 283, 121462. (影响因子：15.3, ESI高被引论文)
8. Chunyu Huang#, Tianfu Zhang#, Yang Li#, Meng Lyu, Meng Suo, Ligang Xia, Lingrong Liu,* Ben Zhong Tang*, Qiqing Zhang* Type-I AIE photosensitizer triggered cascade catalysis system for tumor targeted therapy and postoperative recurrence suppression. Chem. Eng. J. 2022, 446, 136381. (影响因子：13.3)
9. Wei He#, Tianfu Zhang#, Haotian Bai, Ryan T. K. Kwok,* Jacky W. Y. Lam, Ben Zhong Tang* Recent Advances in Aggregation-Induced Emission Materials and Their Biomedical and Healthcare Applications. Adv. Healthcare Mater. 2021, 2101055. (影响因子：11.9)
10. Zheng Zheng#, Tianfu Zhang#, Haixiang Liu#, Yuncong Chen, Ryan T.K. Kwok, Chao Ma, Pengfei Zhang, Herman H. Y. Sung, Ian D. Williams, Jacky W.Y. Lam, Kam Sing Wong, Ben Zhong Tang*. Bright Near-Infrared Aggregation-Induced Emission Luminogens with Strong Two-Photon Absorption, Excellent Organelle Specificity, and Efficient Photodynamic Therapy Potential. ACS Nano 2018, 12, 8145-8159.(影响因子：18.0, ESI高被引论文)
授权专利
1. Bee Luan Khoo, Tianfu Zhang. A Composition And A Method For Diagnosing And Treating Bacterial Infection. (U.S. Patent, filled 11/2021, No. 17/536,193)
2. Ben Zhong Tang, Tianfu Zhang, Jacky W. Y. Lam. Amphiphilic Probes with Aggregation-Induced Emission Characteristics for In Vivo Detection of beta-Amyloid Deposits and In Situ Inhibition of beta-amyloid Aggregation. (U.S. Patent, filled 11/2021, 63274945)
