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邵俊东

发布时间:2022-08-31 浏览次数:

个人概况

姓名:邵俊东          性别:

职称:教授             导师资格:硕导/博导

单位:广州医科大学生物医学工程学院

学历:博士             毕业院校:华南理工大学

招生专业:生物医学工程、生物与医药

电子邮件:shaojundong@gzhmu.edu.cn

通信地址:广东省广州市大学城广州医科大学番禺校区A1-601(2)

 

研究方向

主要从事生物医学材料、纳米诊疗制剂、智能药物递送系统等的研发及其在组织工程、疾病诊断、肿瘤成像与治疗、生物检测、皮肤疾病治疗等领域的应用研究:

1. 仿生生物材料在组织工程中的应用

2. 仿生智能材料 (温敏水凝胶、形状记忆高分子、近红外光响应复合材料)的生物应用

3. 智能精准药物递送系统(靶向纳米药物载体,缓释药物载体)和在肿瘤成像诊断与治疗中的应用

4. 表皮精准给药系统(微针载药贴片和可打印载药贴片)在皮肤疾病(色素异常,皮肤癌)中的应用

5. 新型纳米诊疗制剂研发(纳米药物、贵金属纳米颗粒)与生物成像引导的肿瘤治疗


指导学生获得的科研项目和奖项

第五届全国大学生生物医学工程创新设计竞赛一等奖


社会兼职

1. Frontiers in Chemistry审稿编辑

2. Frontiers in Bioengineering and Biotechnology客座编辑


主持科研/教学项目

1. 广州医科大学“南山学者”高层次人才科研启动经费,2022/07-2027/07200万元,在研,主持。

2. 国家自然科学基金青年科学基金项目,51602204,基于二维材料光热效应的多功能组织工程支架,2017/01-2019/1220万元,已结题,主持。

3. 广东省自然科学基金,2016A030313055,具有光热治疗效果的新型硒化铋/聚乳酸组织工程支架的研发,2016/01-2019/0110万元,已结题,主持。

4. 深圳市科技计划项目(学科布局)基20170133 基于二维异质结构材料的高效非制冷红外光探测器的研究,2018/01-2020/12300 万元(合作方:60 万元),已结题,合作方主持。

5. 深圳市科技计划项目 基础研究(自由探索),JCYJ20170307171050039,基于黑磷光热效应的可降解多功能组织工程支架研究, 2017/06-2019/0530万元,已结题,主持。

6. 中国博士后科学基金面上资助项目,2015M572358,硒化铋/聚乳酸光热纳米纤维支架的构建与医学应用探索,2015/06-2016/095万元,已结题,主持。


部分代表性第一和通讯作者论文

[1] Shao JD, Xie H, Huang H, Li ZB, Sun ZB, Xu YH, Xiao QL, Yu XF*, Zhao YT, Zhang H*, Wang HY, Chu PK*. Biodegradable black phosphorus-based nanospheres for in vivo photothermal cancer therapy. Nature communications, 2016, 7, 12967. (中科院1区,IF=17.694) (735 cites, ESI 0.1% 热点论文入选Nature communications 当月热点论文排行榜第1)

[2] Shao JD, Ruan CS, Xie HH, Li ZB, Wang HY, Chu PK, Yu XF*. Black-phosphorus-incorporated hydrogel as a sprayable and biodegradable photothermal platform for post-surgical treatment of cancer. Advanced Science, 2018, 5, 1700848. (中科院1IF=17.521) (222 cites, ESI 1% 高被引论文入选Wiley 2018年最受关注论文)

[3] Shao JD, Ruan CS, Xie HH, Chu PK, Yu XF*. Photochemical Activity of Black Phosphorus for Near-Infrared Light Controlled In Situ Biomineralization. Advanced Science, 2020, 2000439. (中科院1区,IF=17.521) (26 cites)

[4] Shao JD, Zhang J, Jiang C, et al. Biodegradable titanium nitride MXene quantum dots for cancer phototheranostics in NIR-I/II biowindows. Chemical Engineering Journal, 2020, 400, 126009. (中科院1区,IF=16.744) (64 cites)

[5] Xie HH, Liu MQ, You BH, Luo GH, Chen Y*, Liu BL, Jiang ZY*, Chu PK, Shao JD*, Yu XF. Biodegradable Bi2O2Se Quantum Dots for Photoacoustic ImagingGuided Cancer Photothermal Therapy. Small, 2020, 16, 1905208. (通讯作者,封面文章), (中科院1区,IF=15.153) (47 cites)

[6] Shao JD, Xie HH, Wang HY, Zhou WH, Luo Q, Yu XF*, Chu PK*. 2D material-based nanofibrous membrane for photothermal cancer therapy. ACS Applied Materials & Interfaces, 2018, 10, 1155-1163. (中科院1区,IF=10.383) (26 cites)

[7] Shao JD, Tong LP, Tang SY, Guo ZN, Zhang H, Li PH, Wang HY, Du C*, Yu XF*. PLLA nanofibrous paper-based plasmonic substrate with tailored hydrophilicity for focusing SERS detection. ACS Applied Materials & Interfaces, 2015, 7, 5391-5399. (中科院1区,IF=10.383) (104 cites)

[8] Wang XZ#, Shao JD#, Abd El Raouf M, Xie HH, Huang H, Wang HY, Chu PK, Yu XF*, Yang Y, AbdEl-Aal AM, Mekkawy NH, Miron RJ, Zhang YF*. Near-infrared light-triggered drug delivery system based on black phosphorus for in vivo bone regeneration. Biomaterials, 2018, 179, 164-174. (共同一作) (中科院1区,IF=15.304) (74 cites)

[9] Xie HH#, Shao JD#, Ma YF, Wang JH, Huang H, Yang N, Wang HY, Ruan CS*, Luo YF, Wang QQ, Chu PK, Yu XF*. Biodegradable near-infrared-photoresponsive shape memory implants based on black phosphorus nanofillers. Biomaterials, 2018, 164, 11-21. (共同一作) (中科院1区,IF=15.304) (80 cites)

[10] Shao JD, Chen C, Wang YJ, Chen XF, Du C*. Structure and surface nanomechanics of poly (L-lactide) from thermally induced phase separation process. Applied Surface Science, 2012, 258: 6665-6671. (中科院1区,IF=7.392) (33 cites)

[11] Shao JD, Chen S, Du C*. Citric acid modification of PLLA nano-fibrous scaffolds to enhance cellular adhesion, proliferation and osteogenic differentiation. Journal of Materials Chemistry B, 2015, 3, 5291-5299. (中科院2区,IF=7.571) (20 cites)

[12] Alhiyari Y#, Shao JD#, Han AY, Miller A, Krane JF, Luff M, Momcilovic M, Shackelford D, Gu Z*, St. John MA*. Modular polymer platform as a novel approach to head and neck cancer therapy. Scientific Reports, 2022, 12, 3592. (Co-firstauthors) (JCR 1区,IF=4.996)

[13] Shao JD, Lin L, Tang B, Du C*. Structure and nanomechanics of collagen fibrils in articular cartilage at different stages of osteoarthritis. RSC Advances, 2014, 4, 51165-51170. (中科院3区,IF=4.036) (15 cites)

[14] Shao JD, Wang YJ, Chen XF, Hu XM, Du C*. Nanomechanical properties of poly (l-lactide) nanofibers after deformation. Colloids and Surfaces B: Biointerfaces, 2014, 120, 97-101. (中科院2区,IF=5.999) (7 cites)

[15] Shao JD, Chen C, Wang YJ, Chen XF, Du C*. Early stage structural evolution of PLLA porous scaffolds in thermally induced phase separation process and the corresponding biodegradability and biological property. Polymer Degradation and Stability, 2012, 97: 955-963. (中科院2区,IF=5.204) (57 cites)

[16] Shao JD, Chen C, Wang YJ, Chen XF, Du C*. Early stage evolution of structure and nanoscale property of nanofibers in thermally induced phase separation process. Reactive & Functional Polymers, 2012, 72: 765-772. (中科院2区,IF=4.966) (41 cites)


授权专利

1. 喻学锋; 邵俊东; 谢寒寒; 王怀雨; 一种聚合物包裹的黑磷及其制备方法与应用, 2018-05-01, 中国, 201610729312.5.

2. 喻学锋; 郭志男; 邵俊东; 唐思莹; 一种表面增强拉曼散射基底及其制备方法和应用, 2018-05-01, 中国, 201410805568.0.

3. 喻学锋; 游柏浩; 邵俊东; 杨娜; 一种聚多巴胺修饰的黑磷及其制备方法和应用, 2018-05-15, 中国, 201810461585.5.

4. 邵俊东; 黄鹏; 李星星;一种具有多级结构的微针载药贴片及其制备方法, 2021-11-28, 中国。

5. 邵俊东; 黄鹏; 李星星;一种自发热微针载药贴片及其制备方法, 2021-12-30, 中国。


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